Pharmacogenetics of Asthma Treatment

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Exact Hardy-Weinberg Equilibrium Test for genotype counts, biallelic locus

Introduction

When you click "Calculate", the program will estimate the statistical significance of a test that the genotype counts are in Hardy-Weinberg equilibrium.
Several important things to note:

This software is made available without any kind of guarantee of fitness for any purpose whatsoever. It may NOT work correctly. If you miss the Nobel prize because of my mistake, tough. On the other hand, if you win one, an acknowledgement during your acceptance speech would be appreciated. If you detect reproducible errors, please let our know urgently.

Example

I. Counts

The input to this tool is simply three integer counts represeting the number of heterozygotes, common homozygotes, and rarehomozygotes at a given locus in your dataset. The result is a P-value of blah blah blah .... The numbers given below are used only as an example -- similarity to other datasets, either real or fictional, are purely coincidental:

Heterozygotes
Common Homozygotes
Rare Homozygotes